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A comprehensive study of drugs and their effects on living systems, including the mechanisms of action, therapeutic uses, adverse effects, and interactions.
II. Enumeration Give at least five rights in medication administration.
TRUE OR FALSE
Parasympatholytic medication is used in children and clients with narrow-angle glaucoma.
1 1/2 TO 3 1/2 8.
In inserting rectal suppositories, the nurse should assist the client to a left lateral or left Sims’ position, with the upper leg flexed.
In administering heparin injection, the nurse should massage the site of injection to hasten drug absorption.
Sodium bicarbonate may cause milk-alkali syndrome.
Antitussives should not be administered to the client with a head injury or a postoperative cranial surgery client.
Skeletal muscle relaxant is indicated for clients with cerebral palsy.
Streptokinase
Sustained-released nitrates, the client should be instructed to:
Sulfonamides is contraindicated in children younger than 2 years.
Hepatotoxic medications are avoided with the use of androgens.
Which of the following blood levels that needs to be monitored if the client is receiving Warfarin sodium (Coumadin):
Immunomodulators stimulates the immune system to recognize cancer cells and take action to eliminate or destroy them.
Which of the following is benzodiazepine antagonist:
12. Type of metabolites that does not have pharmacologic action.
Mydriatics are contraindicated in clients with glaucoma because of the risk of decreased intraocular pressure.
Client receiving Nifedipine (Procardia, Adalat, Nifedical) should avoid use or use cautiously with magnesium sulfate, to prevent which of the following?
The nurse should advise the client taking cholinergic medication to take the medication as prescribe.
Mannitol (Osmitrol) is a:
Clients receiving antiemetic should protect from injury.
14. The drug specific target usually a protein located on the surface of a cell membrane or within
Monitor kidney and liver function studies.
Which of the following is not a rapid acting insulin:
Due to immaturity of liver and kidney function in older client, it may lead to accumulation of the drug in the body.
A preparation like an ointment, but thicker and stiff, that penetrates the skin less than an ointment.
The client receiving a laxative need to increase fluid intake.
Pneumococcal conjugate vaccine (PCV) is given orally.
Dr. B. orders a liter of D5W to run this 8-hour shift. The drop factor is 15. What is the drip rate per minute?
Cardiac glycoside is used in clients with cardiogenic shock.
20. Solution injected into intravascular compartment via a vein.
9. It is a maintained concentration of a drug in the plasma during a series of scheduled doses.
The nurse should administer which medication in clients who developed anaphylactic reaction due to antineoplastic medications?
22. An aerosol generator that converts liquid drug solutions or suspensions into aerosol and is powered by compressed air, oxygen, a compressor, or an electrically powered device.
9 MONTHS TO 1 YEAR 9.
Which of the following is a sign and symptoms of dystonia:
Topical glucocorticoids cannot be absorbed into the systemic circulation.
An aqueous solution of sugar often used to disguise unpleasant-tasting drugs.
Monitor for petechiae, ecchymosis, bleeding of the gums, and nosebleeds.
Aluminum hydroxide is used to treat hypophosphatemia.
Cholinergic drug include Bethanechol chloride (Urecholine).
CNS depressants have a calming effect on children with attention-deficit hyperactivity disorder and increase alertness and sensitivity to stimuli.
Which of the following is not correct in magnesium sulfate?
Meperidine hydrochloride (Demerol) and hydromorphone hydrochloride (Dilaudid) should not administered in early labor.
Atypical new generation medication decreases effects of dopamine serotonin and/or norepinephrine at neural membranes.
Neuromuscular blockers is used with anesthetics during surgery to maintain muscle relaxation.
When administering levodopa, instruct the client to avoid excessive vitamin B12 intake.
Acetaminophen (Tylenol) is used to decrease pain and fever.
Placement under the tongue allows a drug to diffuse into the capillary network and to enter the systemic circulations indirectly.
6. The rate and extent to which an administered drug reaches the systemic circulation.
The effects urinary tract antiseptics can also be use for infections outside the urinary tract.
Phenytoin decreases the effectiveness of some birth control pills and can have teratogenic effects if taken during pregnancy.
Which of the following is not used to decrease extrapyramidal side effects:
Monitor liver function tests when a client is taking a skeletal muscle relaxant because neurotoxicity can occur.
______________1. Growth retardation is one of the systemic adverse effects of topical glucocorticoids.
Opioid analgesic
Clients with asthma can use mucolytic agents to increase airway resistance.
Prolonged use of antibiotics can increase the client’s risk of superinfections, or secondary infections.
Eye lubricant add moisture to the eyes.
19. These routes have the highest bioavailability and not subject to first-pass metabolism or harsh GI environment.
Benzodiazepines interact with other CNS medications, producing an additive effect. TRUE
Immunosuppressants used for the following except?
Medication used to treat psoriasis that is contraindicated during pregnancy.
Enteric coated medication can be crush and mix with food if the client has difficulty swallowing.
Medication used to treat psoriasis that is contraindicated in clients with human immunodeficiency virus infection.
Nasal decongestant can be use in client with allergic rhinitis and acute coryza.
When using a bronchodilator inhalant in addition to the steroid inhalant, use the steroid at least 5 minutes prior to the bronchodilator.
PENTAVALENT VACCINE 4.
Sympathomimetic medication is used to treat hypertension, heart failure and cardiac arrest.
Which of the following is not included in estrogen hormonal medications?
Give the rationale of the following nursing intervention for clients receiving medications for cardiovascular system. 2 points each.
Client taking anticholinergic has drug interaction in the following except:
Nursing intervention necessary for client receiving silver sulfadiazine (Silvadene, Thermazene,
If the client receiving immunosuppressants, flowers, plants, fresh fruit, and raw vegetables should be discouraged.
Tamoxifen citrate may cause impotence and gynecomastia in men.
13. The time after administration when the body initially responds to the drug.
Antigout medication should be used cautiously in clients with gastrointestinal disease.
Abrupt withdrawal of adrenergic blockers may lead to:
Requiring increase dose to achieve therapeutic effect.
Mexiletine may be administered with food or antacids.
Which of the following is not a typical cholinergic effect:
PENTAVALENT VACCINE 3.
Anticholinergic medication is also known as cholinergic-blocking agents.
An example of beta adrenergic blockers.
Thrombolytic medication is contraindicated in clients with active internal bleeding.
A medication mixed with alcohol, oil, or soapy emollient and applied to the skin.
9. Which of the following is not an indication of prostaglandin?
An acne product where it decreases androgen activity resulting in decrease production of sebum.
Instruct the client taking lithium (Lithobid) to maintain a fluid intake of six to eight glasses of water a day and an adequate salt intake.
Osmotic medication is used for emergency treatment of glaucoma.
If diarrhea is a problem, avoid hot foods and high-fiber foods.
Prostaglandin is used for:
Which of the following is not a withdrawal symptom of benzodiazepine:
PENTAVALENT VACCINE 5.
In client taking glucocorticoids, the nurse should use this medication with extreme caution in clients with infections.
Toxicity of alpha-adrenergic blockers is treated with:
Positive inotropic and cardiotonic medications are used for:
Administer antiemetics several hours before chemotherapy and for 12 to 48 hours after as prescribed.
3 1/2 MONTH 7.
Mineralocorticoids are used for primary and secondary adrenal sufficiency in Addison’s disease.
Vastus lateralis muscle is the recommended site of intramuscular injection in young adult.
Theophylline is a glucocorticoid medication.
Mydriatics are should not be given in clients with glaucoma.
Buspirone effect takes 3-6 weeks, which is shorter than other anxiolytics.
Clients taking bronchodilators, instruct the client to administer oral medication:
Which immunomodulator agents induce more rapid bone marrow recovery after suppression by chemotherapy?
Sodium nitroprusside should protect from light.
When a medication is intended for the trachea, bronchi, and/or lungs, it is inhaled through the nose.
Adrenergic agonist is for:
The physician orders 500 mg of ibuprofen for a patient and you have 250 mg on hand. How many tablets should be given? ( 5PTS)
Adrenergic agonist is contraindicated in clients with:
An example of alpha adrenergic blockers.
Thyroid hormones control the metabolic rate of tissues and decreases heat production and oxygen consumption of the body.
Topical eye anesthetics are used for anesthesia for eye examinations and surgery or to keep foreign bodies from the eye.
Client receiving antineoplastic medication should initiate bleeding precautions if:
Give the rationale of the following nursing intervention for clients receiving medications for urinary system. 2 points each.
A licensed health professional who prepares, dispenses and advises on medicinal drugs.
Client taking prednisone should monitor glucose and serum potassium levels because it can cause hyperglycemia and hypokalemia.
Which of the following is not a short acting insulin:
Digoxin (Lanoxicaps, Lanoxin) is contraindicated in clients with:
Bethanechol chloride is give only by:
Glucocorticoids should be used with caution in clients with diabetes mellitus.
Anticoagulant is contraindication in clients with myocardial infarction and deep vein thrombosis.
When receiving positive inotropic and cardiotonic medications, the nurse should monitor for?
Immunosuppressants suppresses the immune response and alter antibody formations.
Busulfan (Myleran, Busulfex) may cause:
Vaccines administered intramuscularly in infants are best given in:
BIRTH 2.
In client taking oral contraceptives, advise the client to use an alternate method of birth control when taking antibiotics.
Tricyclic antidepressant clomipramine (Anafranil) may be used to treat obsessive- compulsive disorder.
A flat, round, or oval preparation that dissolves and releases a drug when held in the mouth.
Leukotriene modifiers should be used with caution in clients with impaired hepatic function.
Psychological/physiological need to take a medication.
Which of the following symptoms of anaphylactic reaction due to antineoplastic medications.
Magnesium sulfate is contraindicated in clients with myocardial damage.
The client with HIV or AIDS is at high risk for the development of:
Nursing intervention necessary for client receiving mafenide acetate (Sulfamylon) include:
Which of the following is a sign and symptoms of Akathisia:
Vaccines administered intramuscularly for children 36 months and older are best given in:
The nurse should advise the client taking anticholinergic medication that antacid:
Nitrates are contraindicated in clients with:
Alpha adrenergic blocker should be taken with food or milk.
Instruct the client taking fluoxetine (Prozac) or bupropion (Wellbutrin) to take the medication early in the day.
Ergot alkaloids is contraindicated in clients with the following except:
Physician orders 1500 mg of liquid ibuprofen for a patient. Quantity of Ibuprofen is 500 mg in 1 cc, how much will you administer?
Dopamine decreases the myocardial contractility thus, improving cardiac performance.
Opioids analgesics is used for:
Bethanechol chloride (Urecholine) is not given to a client who has a urinary stricture or obstruction.
Client taking alpha adrenergic blocker should be instructed to change positions slowly.
The onset of drug action in transdermal route is slower than oral route.
5. A scientist that researches new drugs.
High doses of oxytocin may cause hypotension, with:
When applying eye drops, the nurse should instruct the client to apply pressure over the inner canthus next to the nose for 30 to 60 seconds following administration of the medication.
Bile acid sequestrants should use cautiously in clients with suspected bowel obstruction or severe constipation.
Skeletal muscle relaxant is contraindicated in clients with multiple sclerosis and brain attack.
The main side effect of thrombolytic medication is formation of thrombus.
19. Which of the following is an indication of anticholinergic medication.
The antidote for hypertensive crisis in client taking MAOIs, is:
7. Which of the following factors influencing absorption is not included?
Tocolytics produce uterine relaxation and suppress uterine activity.
Unexpected or unique response.
Nitrofurantoin is contraindicated in clients with renal impairment.
Furosemide (Lasix) is a:
The therapeutic drug serum level of lithium is:
Penicillins and cephalosporins should be given separately with aminoglycosides.
When doing subcutaneous injection, the nurse should use z-track technique to avoid injecting the blood vessels.
Antitumor antibiotic medication, pulmonary toxicity can occur with:
For clients taking MAOI, avoid administering the medication in the evening.
Promote a fluid intake of at least 2000 mL/ day.
Which of the following is not a positive symptom of schizophrenia:
Which of the following is not included in atropine toxicity.
Lithium has teratogenic effect during 3rd trimester.
Prostaglandin is administered orally to induce labor.
Acetaminophen
NSAIDs medication is included in antigout medication.
Magnesium sulfate
Clients taking loop diuretics should be advised to:
Clients receiving translingual nitrates (spray), the client should be instructed to:
Thiazide and thiazide-like diuretics should be used with caution in client:
Benzodiazepines should administer at no more than 5 mg/min intravenously to prevent bradycardia.
Cisplatin (Platinol-AQ) may cause:
Offer sips of water before giving sublingual nitrates:
When administering phenytoin intravenously, infuse no faster than 25 to 50 mg/min; otherwise, hypertension and cardiac dysrhythmias could occur.
Leukotriene modifiers are contraindicated in breast feeding mothers.
If gold toxicity occurs, the doctor may prescribe dimercaprol (BAL in oil) to prevent gold excretion.
Magnesium sulfate is used for:
Children receiving the Varicella vaccine should avoid aspirin or aspirin-containing products.
2. The name under which a drug is listed in one of the official publications.
The best route in allergy testing and tuberculosis screening is intradermal route.
Antidiuretic hormones enhances reabsorption of water in the kidneys.
Transmucosal-buccal nitrates, the client should be instructed to:
Toxicities and overdose by the oral route may be overcome with antidotes, such as activated charcoal.
MMR vaccine administration route is:
Metabolites is the product of biotransformation.
Cimetidine (Tagamet) passes the blood-brain barrier.
______________8. Diclofenac sodium (Solaraze) is used in conjunction with blue light photoactivation in treating actinic keratosis.
Neuromuscular blockers
Topical applications includes dermatologic preparations, installations and irrigations.
Antigout medications can increase desired effect by taking aspirin.
Bethanechol chloride (Urecholine)
Returns the body to health.
Oder people who are taking sedatives require higher dosage due to decrease absorption of the drugs.
Fluorouracil (Adrucil) may cause alopecia, stomatitis, diarrhea, phototoxicity reactions, and cerebellar dysfunction.
Monitor for neurotoxicity with vincristine sulfate manifested as:
3. Tocolytics is used for:
Antitumor antibiotic medication, dysrhythmias can occur with:
Instruct the client taking amiodarone to use sunscreen and protective clothing.
15. The pharmacologic effects when the drug produces the same type of response as the physiological or endogenous substance.
______________6. In using sunscreens, products containing PABA need to be used by individuals allergic to benzocaine, sulfonamides, or thiazides.
Instruct the client that cyclophosphamide, when prescribed orally, is:
Parasiticidal prevents worm growth and reproduction (for pinworms).
Inappropriate intake of a medication.
If the client decides to discontinue the contraceptive to become pregnant, recommend that the client use an alternative form of birth control for 2 months after discontinuation.
For clients receiving tricyclic medications should be instructed to avoid alcohol and nonprescription medications.
Clients receiving tocolytics should be positioned on her side.
18. Best route in administering drugs that are poorly absorbed from the GI tract and for agents that are unstable in GI tract.
Glucocorticoids are administered with caution in clients who have inflammatory respiratory conditions.
An antineoplastic medication that affect cells only during a certain phase of the reproductive cycle.
4. It is the metabolic conversion of drug molecules to more water-soluble metabolites or less active form that are more readily excreted.
Bronchodilators are indicated in clients with emphysema and other restrictive airway disease.
Typical antipsychotic medication is given in clients exhibiting alogia.
Pneumococcal conjugate vaccine (PCV) administration route is:
Obtain a drug history before the administration of an opioid analgesic.
An antineoplastic medication that affect cells in any phase of the reproductive cycle.
Phenytoin (Dilantin) is used to treat partial and generalized tonic-clonic seizures.
______________2. Acneiform eruptions is included also in systemic adverse effects of topical glucocorticoids.
Client taking isoniazid should be instructed to monitor for tingling, numbness, or burning of the extremities because these are signs of hepatotoxicity.
17. Tablet held between cheek and gum until dissolved.
Which of the following is a sign and symptoms of Parkinsonism:
3. This name describes the constituents of the drug precisely.
11. Type of metabolites that has a pharmacologic action.
Supports body function until other treatments or the body’s response can take over.
______________7. Client who use Aminolevulinic acid (Levulan Kerastick) should protect the area from sunlight and bright indoor lights.
4. Specialist who often guides the primary care provider in prescribing drugs.
In nasal medication, the client is advised to blow their noses after the administration of nasal sprays.
Take anticonvulsants with food or milk but avoid alcohol.
Cardiac glycosides produce a positive inotropic action, which:
Severe side effect or toxicity.
Hepatitis A vaccine (HepA) administration route is:
The process by which metabolites and drugs are eliminated from the body.
Client receiving magnesium sulfate intravenously, the nurse should call the health care provider if respirations are less than 12 breaths/min.
Instruct the client taking a corticosteroid not to stop the medication abruptly.
One of the fetal contraindications of tocolytics is the gestational age greater than 37 weeks.
Cardiac glycosides produce a negative chronotropic action, which:
Hypersensitive, life-threatening reaction.
Opioid antagonist used to treat respiratory depression from opioid overdose.
1. Assigned by the United States Adopted Names (USAN) Council and is used throughout the drug’s lifetime.
Early signs of digoxin toxicity present as:
Instruct the client about the need for contraception.
Which of the following is a sign and symptoms of tardive dyskinesia:
5. The time interval required for the body’s elimination processes to reduce the concentration of the drug in the body by one-half.
Spironolactone (Aldactone) is a:
The nurse should instruct the client not to use sodium osmotic with older adults or children.
Enoxaparin
When a drug is absorbed from the GI tract, it enters the portal circulation before entering the systemic circulation.
Which of the following damages HIV’s DNA interfering with ability control host DNA?
Dilates the pupils of the eye.
______________3. Organic (chemical) sunscreens absorb UV light.
Methenamine is recommended for acute urinary tract infection.
1. Order: Client is receiving Erythromycin 750 mg, the stock on hand is 250 mg in 5 mL. How many ML should be given. (5 POINTS)
Leukotriene increases bronchoconstriction caused by antigen and reduce airway edema.
Rectal route is considered topical application.
Metered-dose inhaler (MDI) is a handheld nebulizer that can be used by the client to release the medication through a mouthpiece.
Before administering a bolus, the nurse should look up the maximum concentration recommended for the particular drug.
Aspirin should be discontinued 3 to 7 days before surgery.
Administer analgesic as prescribed to client’s receiving ergot alkaloids.
Client’s positive and negative expectations can increase or decrease response of the drug.
Give the rationale of the following nursing intervention for clients receiving medications for respiratory system. 2 points each.
Antithyroid medication is used for hyperthyroidism or Grave’s disease.
10. Placement of drug under the tongue.
Client receiving antineoplastic medication should avoid aspirin-containing products.
In irrigation of the ear, the doctor may prescribe hydrogen peroxide solution.
MMR vaccine protects against measles, mumps, and rubella.
25. Which of the following is nonbenzodiazepine anxiolytic:
______________5. Sunscreen should be reapplied every 30 minutes for increase protection.
Silver sulfadiazine (Silvadene, Thermazene, SSD Cream) systemic effects include leukopenia and interstitial nephritis.
______________4. Keratolytics suppresses DNA synthesis, miotic activity, and cell proliferation.
Also known as one-time order is for medication to be given once at a specified time.
An example of calcium channel blockers.
Montelukast, oral (Singulair) should be taken 1 hour before or 2 hours after meal.
Pilocarpine
Transdermal patch is applied to a hairless, clean area of skin that is subject to excessive movement or wrinkling.
Varicella vaccine administration route is:
The following drug is used for moderate and severe dementia and Alzheimer’s disease.
Antacids is used in clients with peptic ulcer disease and gastroesophageal reflux disease.
1 1/2 TO 3/12 MONTH 6.
Client taking antigout medication should be instructed to avoid foods high in purine.
Common complaint of clients taking an ACE inhibitor.
Edrophonium (Tensilon)
Cures a disease or condition.
A concentrated form of a drug made from vegetables or animals.
Cardiac glycosides
Client who are taking medication through sublingual route should be advised to keep the medication under the tongue until it is absorbed.
Varicella vaccine protects against:
For clients who are taking selective serotonin reuptake inhibitors (SSRI) should be administer with a snack or meal.
Clients taking anticoagulants should not take aspirin or NSAIDS.
Instruct clients with diabetes mellitus using β-adrenergic blockers as an eye medication to monitor blood glucose levels frequently.
BIRTH 1.
The side effects of antineoplastic medication results from its effects in cancer cells.
Antineoplastic medication causes the slow destruction of cells, resulting in the release of uric acid.
21. Injected in tissue just below skin.
Instruct the client taking anxiolytic medication to avoid alcohol and sedatives because:
7. If magnesium sulfate is used for preeclampsia, it may be prescribed:
The vaccines should be stored on a center shelf and not on the door.
Inform the client using eye gel to store the gel at room temperature or in the refrigerator.
8. Most drug metabolites are eliminated in the:
Antihistamine is used for colds and rhinitis.
16. Which of the following is not included in client teaching in medication administration?
RhoGAM should be administered within 72 hours before potential or actual exposure to Rh-positive blood.
_____________10. Coal tar can stain the skin and hair.
This site should be avoided when injecting vaccine in intramuscular route:
Circadian and sleep cycles can also affect drug therapy.
The nurse should administer adrenergic agonist through a large vein.
Which of the following prevents conversion of HIV RNA into HIV DNA?
In administering eye medication, instruct the client to read the medication labels carefully.
In using sunscreens, products containing PABA need to be avoided by individuals allergic to benzocaine, sulfonamides, or thiazides.
Replaces body fluids or substances.
May be carried out indefinitely until an order is written to cancel it.
Give the rationale of the following nursing intervention for clients receiving medications for musculoskeletal system. 2 points each.
A gelatinous container to hold a drug in powder, liquid, or oil form.
______________9. High-dose of anthralin (Dritho-Scalp, Psoriatec) may cause hypercalcemia.
Which immunomodulator slows tumor cell division?
The client receiving antineoplastic medication is instructed to use a soft toothbrush and electric razor to:
Dexamethasone (Maxidex) should not be used for eye abrasions and wounds.
Give the antidote of the following medications. 2 points each.
During the administration of positive inotropic and cardiotonic medications, the nurse should:
Glucocorticoids is intended for acute respiratory attacks.
Which of the following blood levels that needs to be monitored if the client is receiving Heparin sodium:
Benzodiazepines are contraindicated in clients with anxiety.
Tincture of opium can be diluted with 15 to 30 mL of water for administration.
Magnesium sulfate is used with caution in clients with:
Famotidine (Pepcid) and nizatidine (Axid) can be administered with food.
The dosage of a benzodiazepine should be tapered gradually over:
Diazepam (Valium) acts on the CNS to suppress spasticity and affect skeletal muscle directly.
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